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Characterization of the Mitochondrial Genetic Landscape in Abdominal Aortic Aneurysm

Background Abdominal aortic aneurysm (AAA) is a vascular disease with a mortality rate of >80% if ruptured. Mitochondrial dysfunction has been previously implicated in AAA pathogenesis. In this study, we aimed to characterize the mitochondrial genetic landscape in AAA. Methods and Results Whole mito...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Sakshi Vats, Kristina Sundquist, Yanni Li, Xiao Wang, Mun‐Gwan Hong, Jan Sundquist, Moncef Zarrouk, Anders Gottsäter, Ashfaque A. Memon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2023-04-01
Schriftenreihe:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Schlagworte:
aortic aneurysm
abdominal
computational biology
DNA
mitochondrial
genome
Online-Zugang:https://www.ahajournals.org/doi/10.1161/JAHA.122.029248
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