Noninvasive Assessment of β‐Secretase Activity Through Click Chemistry‐Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer's Disease

Abstract Alzheimer's disease (AD), the most prevalent type of dementia, is characterized by a biological process that begins with the development of AD neuropathologic change (ADNPC) while individuals remain asymptomatic. A key molecular hallmark of ADNPC is the accumulation of amyloid‐β plaques. β‐...

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मुख्य लेखकों:	Hyoyong Kim, Junseok Lee, Audrey Qian, You‐Ren Ji, Ryan Zhang, Qixin Hu, Christopher Kazu Williams, Han‐Yu Chuang, Matthew D. Smalley, Yaya Xu, Liang Gao, Mary C. Mayo, Ting Zhang, Edwin M. Posadas, Zaldy S. Tan, Harry V. Vinters, Keith Vossel, Shino Magaki, Yazhen Zhu, Hsian‐Rong Tseng
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Wiley 2025-07-01
श्रृंखला:	Advanced Science
विषय:	Alzheimer's disease liquid biopsy neurodegenerative disease neuronal extracellular vesicle β‐secretase
ऑनलाइन पहुंच:	https://doi.org/10.1002/advs.202415289
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