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Necroptosis plays a role in TL1A-induced airway inflammation and barrier damage in asthma

Abstract Background Airway epithelial cell (AEC) necroptosis contributes to airway allergic inflammation and asthma exacerbation. Targeting the tumor necrosis factor-like ligand 1 A (TL1A)/death receptor 3 (DR3) axis has a therapeutic effect on asthmatic airway inflammation. The role of TL1A in medi...

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Asıl Yazarlar: Xiaofei Liu, Jintao Zhang, Dong Zhang, Yun Pan, Rong Zeng, Changjuan Xu, Shuochuan Shi, Jiawei Xu, Qian Qi, Xueli Dong, Junfei Wang, Tian Liu, Liang Dong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2024-07-01
Seri Bilgileri:Respiratory Research
Konular:
TL1A
Necroptosis
MLKL
Airway inflammation
Tight junction
NF-κB
Online Erişim:https://doi.org/10.1186/s12931-024-02900-4
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