Necroptosis plays a role in TL1A-induced airway inflammation and barrier damage in asthma

Abstract Background Airway epithelial cell (AEC) necroptosis contributes to airway allergic inflammation and asthma exacerbation. Targeting the tumor necrosis factor-like ligand 1 A (TL1A)/death receptor 3 (DR3) axis has a therapeutic effect on asthmatic airway inflammation. The role of TL1A in medi...

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Auteurs principaux:	Xiaofei Liu, Jintao Zhang, Dong Zhang, Yun Pan, Rong Zeng, Changjuan Xu, Shuochuan Shi, Jiawei Xu, Qian Qi, Xueli Dong, Junfei Wang, Tian Liu, Liang Dong
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2024-07-01
Collection:	Respiratory Research
Sujets:	TL1A Necroptosis MLKL Airway inflammation Tight junction NF-κB
Accès en ligne:	https://doi.org/10.1186/s12931-024-02900-4
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