Autophagy attenuates osteoarthritis in mice by inhibiting chondrocyte pyroptosis and improving subchondral bone remodeling

Osteoarthritis (OA) is an age-related degenerative disease characterized by cartilage degeneration and abnormal bone remodeling in the subchondral bone. Autophagy maintains cellular homeostasis by self-phagocytosis. However, the underlying mechanisms of autophagy on the pathological progression of O...

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Bibliografische Detailangaben

Hauptverfasser:	Jiangbo Yan, Gangning Feng, Yong Yang, Dong Ding, Long Ma, Xin Zhao, Xiaolei Chen, Hui Wang, Zhirong Chen, Qunhua Jin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2023-01-01
Schriftenreihe:	Biomolecules & Biomedicine
Schlagworte:	Osteoarthritis chondrocyte autophagy pyroptosis subchondral bone
Online-Zugang:	https://www.bjbms.org/ojs/index.php/bjbms/article/view/7677
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