Improving anti-tumor activity of sorafenib tosylate by lipid- and polymer-coated nanomatrix

In the present study, we select the Sylysia 350 (Sylysia) as mesoporous material, distearoylphosphatidylethanolamine-poly(ethylene glycol)2000 (DSPE-PEG) as absorption enhancer and hydroxy propyl methyl cellulose (HPMC) as crystallization inhibitor to prepare sorafenib tosylate (SFN) nanomitrix (MSN...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Yang Guo, Ting Zhong, Xiao-Chuan Duan, Shuang Zhang, Xin Yao, Yi-Fan Yin, Dan Huang, Wei Ren, Qiang Zhang, Xuan Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2017-01-01
coleção:	Drug Delivery
Assuntos:	sorafenib tosylate nanomatrix poorly water-soluble drugs bioavailability anti-tumor activity
Acesso em linha:	http://dx.doi.org/10.1080/10717544.2016.1245371
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!