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Macrophage‐based delivery of anti‐fibrotic proteins alleviates bleomycin‐induced pulmonary fibrosis in mice

Abstract Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease characterized by chronic, progressive, and fibrotic lung injury. Although remarkable progress has been made toward understanding the pathogenesis of PF, finding more effective treatments for this fatal disease remains...

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Principais autores: Huiying Liu, Cuiping Yang, Yun Gao, Xueli Zhang, Min Wang, Xinting Yu, Weidong Wang, Lixin Xie, Ping Tang, Xiushan Yin, Changqing Bai, Luo Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2023-09-01
Serier:Bioengineering & Translational Medicine
Fag:
bleomycin
CD147
engineered macrophages
idiopathic pulmonary fibrosis
IL‐10
TGF‐β
Online adgang:https://doi.org/10.1002/btm2.10555
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