Cold inducible RNA binding protein promotes fibroblast activation and its inhibition represents a potential therapeutic target in pulmonary fibrosis

Abstract Pulmonary fibrosis is a fatal interstitial lung disease marked by irreversible lung structure destruction. Understanding its molecular mechanisms is essential. Cold-inducible RNA-binding protein (CIRBP), a stress-responsive protein, stabilizes mRNA intracellularly and also acts extracellula...

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Автори:	Yasutaka Mochizuka, Hironao Hozumi, Hirofumi Watanabe, Atsuki Fukada, Hyogo Naoi, Yusuke Inoue, Hideki Yasui, Yuzo Suzuki, Masato Karayama, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Naoki Inui, Takafumi Suda
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Nature Portfolio 2026-02-01
Серія:	Scientific Reports
Предмети:	CIRP Fibroblast Interleukin-6 Toll-like receptor Lung fibrosis Bleomycin
Онлайн доступ:	https://doi.org/10.1038/s41598-026-39649-3
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