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Immune Modulation of NYVAC-Based HIV Vaccines by Combined Deletion of Viral Genes that Act on Several Signalling Pathways

An HIV-1 vaccine continues to be a major target to halt the AIDS pandemic. The limited efficacy of the RV144 phase III clinical trial with the canarypox virus-based vector ALVAC and a gp120 protein component led to the conclusion that improved immune responses to HIV antigens are needed for a more e...

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Bibliografski detalji
Glavni autori: Carmen Elena Gómez, Beatriz Perdiguero, Cristina Sánchez-Corzo, Carlos Oscar S. Sorzano, Mariano Esteban
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2017-12-01
Serija:Viruses
Teme:
Online pristup:https://www.mdpi.com/1999-4915/10/1/7
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