Heterologous combinations of VSV-GP and native-like trimers elicit autologous Tier 2 HIV antibodies in rabbits

Abstract Developing an effective human immunodeficiency virus (HIV) vaccine remains challenging due to difficulties to induce antibodies that neutralize the wide range of HIV-variants. Native-like HIV envelope (Env) trimers in a closed conformation represent promising immunogens. We evaluated the im...

Descripción completa

Detalles Bibliográficos

Autores principales:	Frederik Radvan, Alexandra Hauser, Li-Yun Lin, Sarah Wilmschen-Tober, Marion Schaber, Marta Bermejo-Jambrina, Tariq Oluwakunmi Agbabiaka, David Peterhoff, Lydia Riepler, Nadja Mendrzyk, Anja Beierfuß, Cornelia Speth, Christiane Moog, Dorothee von Laer, Ralf Wagner, Janine Kimpel
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2025-12-01
Colección:	npj Vaccines
Acceso en línea:	https://doi.org/10.1038/s41541-025-01334-3
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!