Single-Cell RNA Sequencing Reveals LEF1-Driven Wnt Pathway Activation as a Shared Oncogenic Program in Hepatoblastoma and Medulloblastoma

(1) Background: Hepatoblastoma and medulloblastoma are two types of pediatric tumors with embryonic origins. Both tumor types can exhibit genetic alterations that affect the β-catenin and Wnt pathways; (2) Materials and Methods: This study used bioinformatics and integrative analysis of multi-omics...

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Bibliografiska uppgifter

Huvudupphov:	Christophe Desterke, Yuanji Fu, Jenny Bonifacio-Mundaca, Claudia Monge, Pascal Pineau, Jorge Mata-Garrido, Raquel Francés
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	MDPI AG 2025-01-01
Serie:	Current Oncology
Ämnen:	LEF1 WNT pluripotency pediatric cancer hepatoblastoma medulloblastoma
Länkar:	https://www.mdpi.com/1718-7729/32/1/35
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