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Deciphering Medulloblastoma: Epigenetic and Metabolic Changes Driving Tumorigenesis and Treatment Outcomes

Background/Objectives: Medulloblastoma is the most common malignant brain tumor in children and comprises four molecular subtypes—WNT, SHH, Group 3, and Group 4—each with distinct genetic, epigenetic, and metabolic features. Increasing evidence highlights the critical role of metabolic reprogramming...

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Principais autores: Jenny Bonifacio-Mundaca, Sandro Casavilca-Zambrano, Christophe Desterke, Íñigo Casafont, Jorge Mata-Garrido
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2025-08-01
Serija:Biomedicines
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Online dostop:https://www.mdpi.com/2227-9059/13/8/1898
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