Acute activation of AMP-activated protein kinase prevents H2O2-induced premature senescence in primary human keratinocytes.
We investigated the effects of AMPK on H(2)O(2)-induced premature senescence in primary human keratinocytes. Incubation with 50 µM H(2)O(2) for 2 h resulted in premature senescence with characteristic increases in senescence-associated ß-galactosidase (SA-gal) staining 3 days later and no changes in...
שמור ב:
| Principais autores: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science (PLoS)
2012-01-01
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| סדרה: | PLoS ONE |
| גישה מקוונת: | http://europepmc.org/articles/PMC3325987?pdf=render |
| תגים: |
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