Immunotherapy with biodegradable nanoparticles encapsulating the oligosaccharide galactose-alpha-1,3-galactose enhance immune tolerance against alpha-gal sensitization in a murine model of alpha-gal syndrome

IgE antibodies against the mammalian oligosaccharide allergen galactose-α-1,3-galactose (αGal) can result in a severe allergic disease known as alpha-gal syndrome (AGS). This syndrome, acquired by tick bites that cause αGal sensitization, leads to allergic reactions after ingestion of non-primate ma...

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Príomhchruthaitheoirí:	Michael N. Saunders, Claudia M. Rival, Mahua Mandal, Kayla Cramton, Laila M. Rad, Katarzyna W. Janczak, Laura A. Williams, Amogh R. Angadi, Jessica J. O’Konek, Lonnie D. Shea, Loren D. Erickson
Formáid:	Artigo
Teanga:	Inglês
Foilsithe / Cruthaithe:	Frontiers Media S.A. 2024-08-01
Sraith:	Frontiers in Allergy
Ábhair:	nanoparticle tolerance IgE sensitization carbohydrates galactose-α-1 3-galactose
Rochtain ar líne:	https://www.frontiersin.org/articles/10.3389/falgy.2024.1437523/full
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