Rejuvenating Hyaline Cartilage with Senescence‐Targeting Si‐ADAM19 Delivery for Osteoarthritis Therapy

Abstract Osteoarthritis (OA) is one of the most common joint degenerative diseases without effective treatment, whose pathology is related to the local accumulation of senescent cells (SnCs). However, existing SnCs‐scavenging drugs “senolytics” may lead to the exhaustion of stem and progenitor cells...

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Detalhes bibliográficos

Principais autores:	Jiasheng Wang, Peng Guo, Dongmei Wu, Junzhi Yi, Qi Jiang, Jiajie Hu, Hongwei Ouyang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-04-01
coleção:	Advanced Science
Assuntos:	a disintegrin and metalloproteinase 19 (ADAM19) cartilage regeneration cellular senescence osteoarthritis(OA) rejuvenating siRNA delivery
Acesso em linha:	https://doi.org/10.1002/advs.202414419
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