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The rs7799039 variant in the leptin gene promoter drives insulin resistance through reduced serum leptin levels

BackgroundThe associations between the rs7799039 variant in the promoter region of the leptin gene (LEP) and the rs1137100, rs1137101, and rs1805094 variants in the exons of the leptin receptor gene (LEPR) with leptin levels and glucose-lipid metabolism markers have been examined across various popu...

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書誌詳細
主要な著者: Yongyan Song, Youjin Zhang, Xinyu Liu, Wang Gong, Yinquan Ai, Binger Shen, Jing Li, Chuan He
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2025-10-01
シリーズ:Frontiers in Endocrinology
主題:
オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fendo.2025.1589575/full
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