Safety Profile and Suicidality Associated with the Use of Esketamine in the Treatment of Major Depressive Disorder in European Countries: An EudraVigilance Database Analysis

<b>Background/Objective:</b> Major depressive disorder (MDD) is a common mental disorder, with a significant portion of patients developing treatment-resistant depression (TRD). Esketamine is an antagonist of the N-methyl-D-aspartate receptor indicated as a nasal spray in combination with other anti...

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Detalhes bibliográficos

Principais autores:	Ilaria Ammendolia, Carmen Mannucci, Emanuela Esposito, Gioacchino Calapai, Mariaconcetta Currò, Paola Midiri, Cristina Mondello, Luigi Cardia, Fabrizio Calapai
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-05-01
coleção:	Pharmaceuticals
Assuntos:	esketamine pharmacovigilance adverse reactions major depressive disorder treatment-resistant depression suicide
Acesso em linha:	https://www.mdpi.com/1424-8247/18/5/702
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