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Safety Profile and Suicidality Associated with the Use of Esketamine in the Treatment of Major Depressive Disorder in European Countries: An EudraVigilance Database Analysis

<b>Background/Objective:</b> Major depressive disorder (MDD) is a common mental disorder, with a significant portion of patients developing treatment-resistant depression (TRD). Esketamine is an antagonist of the N-methyl-D-aspartate receptor indicated as a nasal spray in combination with other anti...

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Principais autores: Ilaria Ammendolia, Carmen Mannucci, Emanuela Esposito, Gioacchino Calapai, Mariaconcetta Currò, Paola Midiri, Cristina Mondello, Luigi Cardia, Fabrizio Calapai
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-05-01
Serier:Pharmaceuticals
Fag:
esketamine
pharmacovigilance
adverse reactions
major depressive disorder
treatment-resistant depression
suicide
Online adgang:https://www.mdpi.com/1424-8247/18/5/702
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