TRIM25 promotes Capicua degradation independently of ERK in the absence of ATXN1L
Abstract Background Aberrations in Capicua (CIC) have recently been implicated as a negative prognostic factor in a multitude of cancer types through the derepression of targets downstream of the mitogen-activated protein kinase (MAPK) signaling cascade, such as oncogenic E26 transformation-specific...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2020-10-01
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| Seria: | BMC Biology |
| Hasła przedmiotowe: | |
| Dostęp online: | http://link.springer.com/article/10.1186/s12915-020-00895-0 |
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