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Ten years of progress and promise of induced pluripotent stem cells: historical origins, characteristics, mechanisms, limitations, and potential applications

The discovery of induced pluripotent stem cells (iPSCs) by Shinya Yamanaka in 2006 was heralded as a major breakthrough of the decade in stem cell research. The ability to reprogram human somatic cells to a pluripotent embryonic stem cell-like state through the ectopic expression of a combination of...

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Autori principali: Adekunle Ebenezer Omole, Adegbenro Omotuyi John Fakoya
Natura: Artigo
Lingua:Inglês
Pubblicazione: PeerJ Inc. 2018-05-01
Serie:PeerJ
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Accesso online:https://peerj.com/articles/4370.pdf
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