The R(−)-Enantiomer of Efonidipine Blocks T-type but Not L-type Calcium Current in Guinea Pig Ventricular Myocardium
In guinea pig ventricular cardiomyocytes, the R(−)-enantiomer of efonidipine concentration-dependently blocked T-type Ca2+ current with 85% inhibition at 1 μM. In contrast, R(−)-efonidipine (1 μM) had no effect on the L-type Ca2+ current and Ca2+ transient in cardiomyocytes and contractile force in...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2004-01-01
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| coleção: | Journal of Pharmacological Sciences |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S1347861319323308 |
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