Selective induction of DNA repair pathways in human B cells activated by CD4+ T cells.
Greater than 75% of all hematologic malignancies derive from germinal center (GC) or post-GC B cells, suggesting that the GC reaction predisposes B cells to tumorigenesis. Because GC B cells acquire expression of the highly mutagenic enzyme activation-induced cytidine deaminase (AID), GC B cells may...
Na minha lista:
| Principais autores: | , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2010-12-01
|
| Serier: | PLoS ONE |
| Online adgang: | http://europepmc.org/articles/PMC3002972?pdf=render |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|
