B cell receptor signaling drives APOBEC3 expression via direct enhancer regulation in chronic lymphocytic leukemia B cells

Abstract Constitutively activated B cell receptor (BCR) signaling is a primary biological feature of chronic lymphocytic leukemia (CLL). The biological events controlled by BCR signaling in CLL are not fully understood and need investigation. Here, by analysis of the chromatin states and gene expres...

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Detaylı Bibliyografya
Asıl Yazarlar:	Zhiquan Wang, Huihuang Yan, Justin C. Boysen, Charla R. Secreto, Renee C. Tschumper, Dania Ali, Qianqian Guo, Jian Zhong, Jiaqi Zhou, Haiyun Gan, Chuanhe Yu, Diane F. Jelinek, Susan L. Slager, Sameer A. Parikh, Esteban Braggio, Neil E. Kay
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Nature Publishing Group 2022-07-01
Seri Bilgileri:	Blood Cancer Journal
Online Erişim:	https://doi.org/10.1038/s41408-022-00690-w
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!

B cell receptor signaling drives APOBEC3 expression via direct enhancer regulation in chronic lymphocytic leukemia B cells

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