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B cell receptor signaling drives APOBEC3 expression via direct enhancer regulation in chronic lymphocytic leukemia B cells

Abstract Constitutively activated B cell receptor (BCR) signaling is a primary biological feature of chronic lymphocytic leukemia (CLL). The biological events controlled by BCR signaling in CLL are not fully understood and need investigation. Here, by analysis of the chromatin states and gene expres...

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Principais autores: Zhiquan Wang, Huihuang Yan, Justin C. Boysen, Charla R. Secreto, Renee C. Tschumper, Dania Ali, Qianqian Guo, Jian Zhong, Jiaqi Zhou, Haiyun Gan, Chuanhe Yu, Diane F. Jelinek, Susan L. Slager, Sameer A. Parikh, Esteban Braggio, Neil E. Kay
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2022-07-01
סדרה:Blood Cancer Journal
גישה מקוונת:https://doi.org/10.1038/s41408-022-00690-w
תגים: הוספת תג
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