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P16 | INTEGRATED p53 ISOFORM EXPRESSION DEFINES NOVEL PROGNOSTIC SUBGROUPS IN MULTIPLE MYELOMA

Introduction. In multiple myeloma (MM), TP53 abnormalities, including deletions and mutations, are well-established drivers of high-risk disease. Beyond full-length p53 (p53FL), alternative p53 isoforms modulate p53 transcriptional activity, cellular stress responses, and tumor behavior. However, t...

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Auteurs principaux: E. Borsi, A. Vitale, V. Solli, V. Meixian Vuong, M. Martello, I. Vigliotta, S. Armuzzi, A. Poletti, B. Taurisano, A. Varacalli, G. Mazzocchetti, A. Croce, I. Pistis, E. Zamagni, P. Tacchetti, I. Rizzello, M. Cavo, C. Terragna
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2026-04-01
Collection:Haematologica
Accès en ligne:https://haematologica.org/article/view/14089
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