P16 | INTEGRATED p53 ISOFORM EXPRESSION DEFINES NOVEL PROGNOSTIC SUBGROUPS IN MULTIPLE MYELOMA
Introduction. In multiple myeloma (MM), TP53 abnormalities, including deletions and mutations, are well-established drivers of high-risk disease. Beyond full-length p53 (p53FL), alternative p53 isoforms modulate p53 transcriptional activity, cellular stress responses, and tumor behavior. However, t...
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| Autori principali: | , , , , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Ferrata Storti Foundation
2026-04-01
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| Serie: | Haematologica |
| Accesso online: | https://haematologica.org/article/view/14089 |
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