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Breaching the Bacterial Envelope: The Pivotal Role of Perforin-2 (MPEG1) Within Phagocytes

The membrane attack complex (MAC) of the complement system and Perforin-1 are well characterized innate immune effectors. MAC is composed of C9 and other complement proteins that target the envelope of gram-negative bacteria. Perforin-1 is deployed when killer lymphocytes degranulate to destroy vira...

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Autors principals: Leidy C. Merselis, Zachary P. Rivas, George P. Munson
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021-02-01
Col·lecció:Frontiers in Immunology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fimmu.2021.597951/full
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