A Key Motif in the Cholesterol-Dependent Cytolysins Reveals a Large Family of Related Proteins
ABSTRACT The cholesterol-dependent cytolysins (CDCs) are bacterial, β-barrel, pore-forming toxins. A central enigma of the pore-forming mechanism is how completion of the prepore is sensed to initiate its conversion to the pore. We identified a motif that is conserved between the CDCs and a diverse...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2020-10-01
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| coleção: | mBio |
| Assuntos: | |
| Acesso em linha: | https://journals.asm.org/doi/10.1128/mBio.02351-20 |
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