A cross-sectional study of oxidative stress pathway genotypes and their interactions with environmental pollutant levels identifies associations with gene expression and lung functionResearch in context

Summary: Background: Asthma is a heterogeneous disease influenced by genetic and environmental factors. Fine particulate matter (PM2.5) exacerbates asthma, likely through oxidative stress pathways, but whether genetic variation modifies this effect remains unclear. Methods: We analysed data on 948...

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Detalles Bibliográficos

Principais autores:	Shuangjia Xue, Seyed Mehdi Nouraie, Jiebiao Wang, Xingnan Li, Deborah Meyers, Eugene R. Bleecker, Victor E. Ortega, Mario Castro, Loren C. Denlinger, Serpil Erzurum, Elliot Israel, Prescott Woodruff, Wendy C. Moore, Stephanie Christenson, John Fahy, Kaharu Sumino, Nizar Jarjour, Bruce Levy, Sally E. Wenzel
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2026-07-01
Series:	EBioMedicine
Assuntos:	Pollution Asthma Genexenvironment PM2.5 Spirometry
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2352396426002173
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