Mitochondrial Lon-induced mtDNA leakage contributes to PD-L1–mediated immunoescape via STING-IFN signaling and extracellular vesicles

Background Mitochondrial Lon is a chaperone and DNA-binding protein that functions in protein quality control and stress response pathways. The level of Lon regulates mitochondrial DNA (mtDNA) metabolism and the production of mitochondrial reactive oxygen species (ROS). However, there is little info...

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Үндсэн зохиолчид:	Tsung-Hsien Chuang, An Ning Cheng, Li-Chun Cheng, Cheng-Liang Kuo, Yu Kang Lo, Han-Yu Chou, Chung-Hsing Chen, Yi-Hao Wang, Shih-Jung Cheng, Alan Yueh-Luen Lee
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMJ Publishing Group 2020-10-01
Цуврал:	Journal for ImmunoTherapy of Cancer
Онлайн хандалт:	https://jitc.bmj.com/content/8/2/e001372.full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!