p75 neurotrophin receptor shapes the dynamics of adult hippocampal neurogenesis in Alzheimer’s disease

Abstract Background Alzheimer’s Disease (AD) is a neurodegenerative disorder primarily characterized by memory loss and cognitive decline. The AD-driven impairment of adult hippocampal neurogenesis - the process of generating new neurons in the dentate gyrus - is strongly implicated in this cognitiv...

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Principais autores:	Maria Anna Papadopoulou, Konstantina Chanoumidou, Maria Peteinareli, Electra Tsaglioti, Konstantina Michalaki, Matthieu D. Lavigne, Ioannis Charalampopoulos
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-02-01
Colecção:	Alzheimer’s Research & Therapy
Assuntos:	Hippocampal adult neurogenesis P75 neurotrophin receptor Alzheimer’s disease Dentate gyrus Neural stem cells Human neural stem cells
Acesso em linha:	https://doi.org/10.1186/s13195-026-01989-7
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