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Excess cerebellar granule neurons induced by the absence of p75NTR during development elicit social behavior deficits in mice

IntroductionRecently, the cerebellum has been implicated with non-motor functions, including cognitive and emotional behavior. Anatomical and functional studies demonstrate bidirectional cerebellar connections with brain regions involved in social cognition. Cerebellar developmental abnormalities an...

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Principais autores: Juan Pablo Zanin, Mansi A. Pandya, Diego Espinoza, Wilma J. Friedman, Michael W. Shiflett
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-05-01
Serier:Frontiers in Molecular Neuroscience
Fag:
p75NTR
granule cell precursor (GCPs)
neurotrophins
cerebellum
social behavior
Online adgang:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1147597/full
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