Activation of transient receptor potential vanilloid 4 increases NMDA-activated current in hippocampal CA1 pyramidal neurons

The glutamate excitotoxicity, mediated through N-methyl-D-aspartate receptors (NMDARs), plays an important role in cerebral ischemia injury. Transient receptor potential vanilloid 4 (TRPV4) can be activated by multiple stimuli that may happen during stroke. The present study evaluated the effect of...

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Autors principals:	Lin eLi, Weijun eQu, Libin eZhou, Zihong eLu, Penghui eJie, Lei eChen, Ling eChen
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2013-03-01
Col·lecció:	Frontiers in Cellular Neuroscience
Matèries:	Phosphorylation cerebral ischemia NMDA receptor TRPV4 NR2B subunit excitotoxity
Accés en línia:	http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00017/full
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