NR2B antagonist CP-101,606 abolishes pitch-mediated deviance detection in awake rats

Schizophrenia patients exhibit a decreased ability to detect change in their auditory environment as measured by auditory event related potentials such as mismatch negativity. This deficit has been linked to abnormal NMDA neurotransmission since, among other observations, non-selective channel block...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Siva eDigavalli, Ping eChen, Yili eYang, Yu-Wen eLi, Rick ePieschl, Michael K Ahlijanian
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2014-08-01
Цуврал:	Frontiers in Psychiatry
Нөхцлүүд:	Ketamine mismatch negativity (MMN) NMDA receptor deviance detection NR2B subunit CP-101606
Онлайн хандалт:	http://journal.frontiersin.org/Journal/10.3389/fpsyt.2014.00096/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!