Metabolic reprogramming during human neuron differentiation indicates glutaminase as a key determinant in Fragile X syndrome

Summary: Metabolic homeostasis gone awry is a contributor to, if not an underlying cause of, several neurologic disorders. Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by a trinucleotide repeat expansion in FMR1 and consequent loss of the encoded protein FMRP, which results in do...

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Үндсэн зохиолчид:	Sneha Shah, Daniel Barnes, Botao Liu, Tenzin Tseyang, Thang Do, Jodi L. Bubenik, Suna Jung, Mina N. Anadolu, Maria P. Ivshina, Verónica Martínez-Cerdeño, Elizabeth Berry-Kravis, Maurice S. Swanson, Jessica B. Spinelli, Joel D. Richter
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2026-01-01
Цуврал:	Cell Reports
Нөхцлүүд:	CP: neuroscience CP: metabolism
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2211124725016298
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!