R-spondin1 Controls Muscle Cell Fusion through Dual Regulation of Antagonistic Wnt Signaling Pathways

Wnt-mediated signals are involved in many important steps in mammalian regeneration. In multiple cell types, the R-spondin (Rspo) family of secreted proteins potently activates the canonical Wnt/β-catenin pathway. Here, we identify Rspo1 as a mediator of skeletal muscle tissue repair. First, we show...

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Detalhes bibliográficos

Principais autores:	Floriane Lacour, Elsa Vezin, C. Florian Bentzinger, Marie-Claude Sincennes, Lorenzo Giordani, Arnaud Ferry, Robert Mitchell, Ketan Patel, Michael A. Rudnicki, Marie-Christine Chaboissier, Anne-Amandine Chassot, Fabien Le Grand
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2017-03-01
coleção:	Cell Reports
Assuntos:	skeletal muscle canonical Wnt signaling non-canonical Wnt signaling R-spondin regeneration muscle satellite cell
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124717302176
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