Live Attenuated Vaccines against Tuberculosis: Targeting the Disruption of Genes Encoding the Secretory Proteins of Mycobacteria

Tuberculosis (TB), a chronic infectious disease affecting humans, causes over 1.3 million deaths per year throughout the world. The current preventive vaccine BCG provides protection against childhood TB, but it fails to protect against pulmonary TB. Multiple candidates have been evaluated to either...

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Detalhes bibliográficos

Principais autores:	Raja Veerapandian, Shrikanth S. Gadad, Chinnaswamy Jagannath, Subramanian Dhandayuthapani
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-05-01
coleção:	Vaccines
Assuntos:	tuberculosis live attenuated vaccines (LAVs) gene knockout <i>Mycobacterium tuberculosis</i> BCG secretory antigens
Acesso em linha:	https://www.mdpi.com/2076-393X/12/5/530
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