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Live Attenuated Vaccines against Tuberculosis: Targeting the Disruption of Genes Encoding the Secretory Proteins of Mycobacteria

Tuberculosis (TB), a chronic infectious disease affecting humans, causes over 1.3 million deaths per year throughout the world. The current preventive vaccine BCG provides protection against childhood TB, but it fails to protect against pulmonary TB. Multiple candidates have been evaluated to either...

Celý popis

Uloženo v:
Hlavní autoři: Raja Veerapandian, Shrikanth S. Gadad, Chinnaswamy Jagannath, Subramanian Dhandayuthapani
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2024-05-01
Edice:Vaccines
Témata:
tuberculosis
live attenuated vaccines (LAVs)
gene knockout
<i>Mycobacterium tuberculosis</i>
BCG
secretory antigens
On-line přístup:https://www.mdpi.com/2076-393X/12/5/530
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