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Caffeic acid phenethyl ester alleviates 1,2-dichloroethane-induced toxic cerebral edema: central and peripheral mechanisms

Background1,2-Dichloroethane (1,2-DCE) is a widespread environmental contaminant as well as a frequent occupational hazard. Given that inflammation and oxidative stress are key mechanisms in 1,2-DCE-induced cerebral edema, we investigated the efficacy of caffeic acid phenethyl ester (CAPE), a natura...

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Principais autores: Yue Sun, Bo Yin, Shubei He, Luxin Miao, Jinhan Yang, Yan Wang, Xiaoxia Jin
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2026-01-01
Series:Frontiers in Pharmacology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fphar.2025.1734227/full
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