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Human umbilical cord mesenchymal stem cells mitigate A1 astrocyte neuroinflammation induced by 1,2-dichloroethane via ERBB pathway inhibition

1,2-Dichloroethane (1,2-DCE), a prevalent industrial and environmental contaminant, induces toxic encephalopathy through inhalation, leading to neurotoxic effects and inflammation-driven brain edema. Human umbilical cord mesenchymal stem cells (HUCMSCs) secrete bioactive factors, including miRNAs, p...

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Principais autores: Jiaxin Du, Yizhou Zhong, Bingchi Fan, Xiaohong Yang, Rongyi Ye, Yuji Huang, Zhiming Li, Boxuan Liang, Hongyi Xian, Yanhong Deng, Xiyun Huang, Xiaoqing Chen, Congying Shi, Xibao Yu, Banghua Wu, Xingfen Yang, Zhenlie Huang
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-12-01
Serier:Ecotoxicology and Environmental Safety
Fag:
1,2-Dichloroethane
Exosome
miRNAs
HUCMSCs
REPS2
Astrocyte activation
Online adgang:http://www.sciencedirect.com/science/article/pii/S0147651324014416
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