Homomeric and Heteromeric Aβ Species Exist in Human Brain and CSF Regardless of Alzheimer’s Disease Status and Risk Genotype

Background: A fundamental question in Alzheimer’s disease (AD) is whether amyloid-β (Aβ) peptides and their deposition in the brain signify a direct pathological role or they are mere outcome of the disease pathophysiological events affecting neuronal function. It is therefore important to decipher...

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Главные авторы:	Erica Lana, Anna Gellerbring, Sabrina Jung, Agneta Nordberg, Christina Unger Lithner, Taher Darreh-Shori
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2019-07-01
Серии:	Frontiers in Molecular Neuroscience
Предметы:	Alzheimer’s disease homomeric and heteromeric amyloid-β apolipoprotein E cholinesterases cholinergic signaling
Online-ссылка:	https://www.frontiersin.org/article/10.3389/fnmol.2019.00176/full
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