A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase

Abstract Background Based on in vitro and in vivo rat experiments, the newly developed acetylcholinesterase (AChE) reactivator, K203, appears to be much more effective in the treatment of tabun poisonings than currently fielded oximes. Methods To determine if this reactivating efficacy would extend...

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Detalhes bibliográficos

Principais autores:	Kamil Kuca, Kamil Musilek, Daniel Jun, Jana Zdarova-Karasova, Eugenie Nepovimova, Ondrej Soukup, Martina Hrabinova, John Mikler, Tanos C. C. Franca, Elaine F. F. Da Cunha, Alexandre A. De Castro, Martin Valis, Teodorico C. Ramalho
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2018-02-01
Colecção:	BMC Pharmacology and Toxicology
Assuntos:	Antidotes Chemical warfare agents Poisoning Treatment Reactivator Oxime
Acesso em linha:	http://link.springer.com/article/10.1186/s40360-018-0196-3
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