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Electropharmacological profile of an atrial-selective sodium channel blocker acehytisine assessed in the isoflurane-anesthetized guinea-pig model

Experimental evidence regarding the risk of proarrhythmic potential of acehytisine is limited. We assessed its electropharmacological effect together with proarrhythmic potential at intravenous doses of 4 and 10 mg/kg (n = 6) using isoflurane-anesthetized guinea pigs in comparison with that of bepri...

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Hlavní autoři: Xin Cao, Yoshinobu Nagasawa, Chengshun Zhang, Hanxiao Zhang, Megumi Aimoto, Akira Takahara
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019-12-01
Edice:Journal of Pharmacological Sciences
On-line přístup:http://www.sciencedirect.com/science/article/pii/S134786131935724X
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