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Making sense of invisible densities in single-particle cryo-EM

In the era of single-particle cryogenic electron microscopy (cryo-EM) and AI-driven protein structure prediction, obtaining high-resolution protein structures, either experimentally or computationally, has become increasingly routine. Yet studying and understanding protein dynamics remains challengi...

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Principais autores: Xiaoxuan Lin, Yifan Cheng
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2026-05-01
Serier:IUCrJ
Fag:
cryo-em
protein structures
protein dynamics
hydrogen–deuterium exchange mass spectrometry
Online adgang:https://journals.iucr.org/paper?S2052252526002952
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