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Identification of pyrC gene as an immunosuppressive factor in Francisella novicida infection

Francisella tularensis, a bacterial causative agent of the zoonosis tularemia, is highly pathogenic to humans. The pathogenicity of this bacterium is characterized by intracellular growth in immune cells, like macrophages, and host immune suppression. However, the detailed mechanism of immune suppre...

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Principais autores: Takemasa Nakamura, Takashi Shimizu, Ryo Ikegaya, Akihiko Uda, Kenta Watanabe, Masahisa Watarai
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2022-10-01
叢編:Frontiers in Cellular and Infection Microbiology
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在線閱讀:https://www.frontiersin.org/articles/10.3389/fcimb.2022.1027424/full
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