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Identification of pyrC gene as an immunosuppressive factor in Francisella novicida infection

Francisella tularensis, a bacterial causative agent of the zoonosis tularemia, is highly pathogenic to humans. The pathogenicity of this bacterium is characterized by intracellular growth in immune cells, like macrophages, and host immune suppression. However, the detailed mechanism of immune suppre...

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Bibliografiske detaljer
Principais autores: Takemasa Nakamura, Takashi Shimizu, Ryo Ikegaya, Akihiko Uda, Kenta Watanabe, Masahisa Watarai
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-10-01
Serier:Frontiers in Cellular and Infection Microbiology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fcimb.2022.1027424/full
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