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HSF1: Primary Factor in Molecular Chaperone Expression and a Major Contributor to Cancer Morbidity

Heat shock factor 1 (HSF1) is the primary component for initiation of the powerful heat shock response (HSR) in eukaryotes. The HSR is an evolutionarily conserved mechanism for responding to proteotoxic stress and involves the rapid expression of heat shock protein (HSP) molecular chaperones that pr...

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Principais autores: Thomas L. Prince, Benjamin J. Lang, Martin E. Guerrero-Gimenez, Juan Manuel Fernandez-Muñoz, Andrew Ackerman, Stuart K. Calderwood
格式: Artigo
語言:Inglês
出版: MDPI AG 2020-04-01
叢編:Cells
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在線閱讀:https://www.mdpi.com/2073-4409/9/4/1046
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