HSF1: Primary Factor in Molecular Chaperone Expression and a Major Contributor to Cancer Morbidity

Heat shock factor 1 (HSF1) is the primary component for initiation of the powerful heat shock response (HSR) in eukaryotes. The HSR is an evolutionarily conserved mechanism for responding to proteotoxic stress and involves the rapid expression of heat shock protein (HSP) molecular chaperones that pr...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Thomas L. Prince, Benjamin J. Lang, Martin E. Guerrero-Gimenez, Juan Manuel Fernandez-Muñoz, Andrew Ackerman, Stuart K. Calderwood
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2020-04-01
Schriftenreihe:	Cells
Schlagworte:	heat shock factor 1 HSF1 cancer heat shock proteins HSPs molecular chaperones
Online-Zugang:	https://www.mdpi.com/2073-4409/9/4/1046
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