A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with myocardial infarction in type 2 diabetic patients

Abstract Background Myocardial infarction is the main mortality cause in patients with type 2 diabetes (T2DM). Endothelial dysfunction due to reduced bioavailability of nitric oxide (NO) is an early step of atherogenesis. Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of NO synthesis,...

Полное описание

Библиографические подробности

Главные авторы:	Gaia Chiara Mannino, Serena Pezzilli, Carolina Averta, Anastasia Fuoco, Rosangela Spiga, Elettra Mancuso, Concetta Di Fatta, Francesco Perticone, Sabrina Prudente, Vincenzo Trischitta, Francesco Andreozzi, Giorgio Sesti
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2019-08-01
Серии:	Cardiovascular Diabetology
Предметы:	Asymmetric dimethylarginine Myocardial infarction Dimethylarginine dimethylaminohydrolase Type 2 diabetes rs9267551
Online-ссылка:	http://link.springer.com/article/10.1186/s12933-019-0906-1
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!