The enhanced cancer nanovaccine by bidirectionally blocking CXCL12/CXCR4 axis to inhibit the recurrence and metastasis of triple-negative breast cancer
Abstract In situ cancer vaccine is a new method for cancer immunotherapy, however, the local immunosuppressive microenvironment of cancer tissue limits its immune response and therapeutic efficacy. The CXCL12/CXCR4 axis plays a key role in forming an immunosuppressive microenvironment. In this study...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2025-11-01
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| Serier: | Molecular Cancer |
| Fag: | |
| Online adgang: | https://doi.org/10.1186/s12943-025-02496-3 |
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